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Hormones

Hormones play a crucial role in our bodies, regulating everything from our mood and appetite to our metabolism and muscle growth. For individuals interested in improving their fitness, understanding the impact hormones have on the body is essential. Whether you are a seasoned athlete or a beginner, knowing how hormones affect your body can help you achieve your fitness goals more efficiently and effectively.

As we age (particularly after age 40), hormones start to decline. This means, you might start to feel the effects of hormone imbalance either physically, emotionally, or both. For some, it might be stubborn weight accumulation in the midsection and lower energy. For women, menstrual cycles start to change; and or men they might first notice a change in ability to put on muscle mass, motivation or drive, or change in libido.

Remember when you were in your 20s, and you could eat anything, do anything, and you not only felt amazing, but didn’t worry about gaining fat when you looked at a piece of bread?! By rebalancing hormones through nutrition, supplements, hormone therapies, or peptides, we can assist your body in helping you feel and look your best at any age.  

Testosterone is known and the “Male Hormone”. Produced by the testes in men, it plays a crucial role in everyday lives. Testosterone exists naturally at a much higher quantity in men than women, but is still very important in women as well.

The lab range is wide and although you may still be in range (and your doctor may tell you it's normal), it could be low enough to still cause symptoms of testosterone deficiency. In men, testosterone declines with age, by up to 1% per year after the age of 40. Low testosterone has been associated with elevated CRP levels and higher risk of cardiovascular diseases, such as atherosclerosis and coronary artery disease, depression, inability to gain muscle, low libido and sexual dysfunction.

Testosterone is important for both men and women. You may think of testosterone as only the sex hormone that makes you horny, but It is also essential for muscle growth, energy, cardiovascular, health, motivation, and concentration. For men Testosterone starts to decline rapidly after age 30.


Low T usually becomes the cause of ED at levels below 300. However libido is greatly affected by higher (but still lower than optimal) levels. In order to maintain your health physically, mentally, emotionally, and sexually as you age, maintaining optimal testosterone levels is crucial.

Signs you may be low in Testosterone:

✅ Fatigue
✅ Weight gain
✅ Difficulty gaining muscle
✅ Low mood
✅ Lack of libido
✅ Sexual dysfunction
✅ Insomnia
✅ Low motivation
✅ Trouble concentrating 



Testosterone Replacement Therapy (TRT)

TRT can serve as an effective option for men suffering from Low T. Though results may vary for each man, by optimizing testosterone to healthy levels the body can be replenished of this crucial hormone so that life can once again be lived with passion and purpose.

If you are suffering from a testosterone deficiency, you may experience the following benefits of TRT:

✅ Rise in energy levels
✅ Increased stamina and endurance
✅ Enhanced and more defined muscle mass
✅ Weight loss
✅ Improved cognitive abilities (sharper and more focused)
✅ Increased sense of well-being
✅ Decreased risk of cardiovascular disease and depression
✅ Improved sex drive
✅ Increased confidence

Nearly all concerns of safety for testosterone replacement therapy, or any other hormone replacement therapy procedure in San Diego, can be addressed by receiving conclusive testing from a trusted and certified men’s health specialist. That’s why testing is always the first step in our process to ensure that not only are patients receiving the appropriate dose of TRT, but that only qualified patients with a real testosterone deficiency are being treated.


What causes Low T?


There can be many factors which can cause lower testosterone other than just age, which is why Dr. Sef does a thorough medical and lifestyle intake, as well as comprehensive labs and not just Testosterone alone. Here are some factors that should always be investigated, but often get overlooked:

✅ Nutrient/vitamin deficiencies
✅ Environmental chemical exposure
✅ Sleep
✅ Stress
✅ Diet
✅ Gut Health
✅ Inflammation
✅ Heavy metals
✅ Genetics
✅ Other hormone imbalances 

Human Growth Hormone declines in adulthood, by about 10% each decade just due to natural aging, inadequate sleep, poor diet/lifestyle, and stress. Growth hormone is most reliantly tested through IGF-1.

Signs of Growth Hormone insufficiency:

✅ Decreased energy levels
✅ Increased body fat
✅ Decreased muscle tone
✅ Poor recovery following workouts
✅ Anxiety, depression, or reduced sense of wellbeing
✅ Decreased bone density
✅ Insulin resistance or Type 2 diabetes 

DHEA, or dehydroepiandrosterone, is a naturally occurring hormone produced by the adrenal glands. It serves as a precursor to several other hormones, including testosterone and estrogen, and plays a vital role in maintaining overall vitality and well-being.

DHEA levels peak during early adulthood and gradually decline with age. It has been linked to various health benefits, including improved energy levels, enhanced mood, increased muscle strength, and better cognitive function. As a result, many people consider DHEA supplementation to support their vitality and overall quality of life.

One of the key functions of DHEA is its role in the production of sex hormones. By serving as a precursor, it contributes to the synthesis of testosterone and estrogen, which are essential for reproductive health, libido, and sexual function. Adequate levels of these hormones are crucial for maintaining vitality and vigor.

Additionally, DHEA is believed to have anti-aging properties. It has been associated with increased muscle mass, decreased body fat, and improved bone density, which are typically affected by the aging process. By promoting muscle strength and reducing age-related decline, DHEA may help individuals maintain an active and energetic lifestyle.

Furthermore, DHEA has been linked to cognitive function and mood regulation. Some studies suggest that optimal DHEA levels are associated with improved memory, mental clarity, and overall cognitive performance. It may also play a role in reducing symptoms of depression and enhancing a sense of well-being. 

Pregnenolone is a natural hormone and precursor to various other hormones in the body, including progesterone, testosterone, estrogen, and cortisol. It is synthesized from cholesterol primarily in the adrenal glands, but it is also produced in the brain, liver, and other tissues. Pregnenolone plays a crucial role in maintaining vitality and overall well-being.

One of the primary functions of pregnenolone is its role in hormone production. It serves as a precursor for the synthesis of other hormones, including sex hormones such as testosterone and estrogen. These hormones are essential for reproductive health, libido, and overall vitality. Adequate levels of pregnenolone support the production of these hormones, contributing to a healthy balance and optimal functioning of the body.

Furthermore, pregnenolone is involved in the regulation of stress response. It acts as a precursor for cortisol, a hormone that helps the body respond to stress. By supporting cortisol production, pregnenolone plays a role in managing stress levels, which can have a significant impact on overall vitality. Chronic stress can lead to fatigue, reduced energy levels, and decreased overall well-being. Therefore, maintaining appropriate pregnenolone levels is important for managing stress and promoting vitality.

Pregnenolone is also believed to have neuroprotective properties. It has been associated with enhanced cognitive function, improved memory, and increased mental clarity. Some studies suggest that pregnenolone supplementation may have a positive impact on age-related cognitive decline and neurodegenerative disorders. By supporting brain health, pregnenolone contributes to overall vitality and quality of life.

It's worth noting that individual responses to pregnenolone supplementation can vary, and its use should be approached with caution. Consulting with a healthcare professional is advised before considering pregnenolone supplementation, as it may interact with certain medications or have potential side effects.

Estrogen is a group of hormones that play crucial roles in both men and women, though their levels and functions differ between the sexes. In women, estrogen is primarily responsible for the development and regulation of the female reproductive system, including the growth of breasts, regulation of the menstrual cycle, and support of pregnancy. It also contributes to maintaining bone density and has impacts on mood, cognition, and cardiovascular health.

In men, although estrogen is present in lower amounts compared to women, it still serves essential functions. It is formed from testosterone through the process of aromatization. Estrogen helps in bone health by maintaining bone density and preventing osteoporosis. It also plays a role in modulating sperm production and may influence sexual function.

The importance of estrogen in both sexes lies in its regulatory effects on various physiological processes beyond reproductive functions. In women, proper estrogen levels are critical for fertility and menstrual regularity. During pregnancy, estrogen supports the growth and development of the fetus. Estrogen also helps maintain healthy vaginal tissues and lubrication.

For men, estrogen contributes to the balance between testosterone and other hormones, impacting overall hormonal health. Adequate estrogen levels are essential for maintaining bone density, preventing bone loss, and reducing the risk of fractures. Additionally, estrogen may have cardioprotective effects by helping maintain healthy blood vessel function and cholesterol levels.

However, like any hormone, the levels of estrogen need to be carefully balanced. Too much or too little estrogen can lead to various health issues. High estrogen levels in men may cause symptoms like gynecomastia (enlargement of breast tissue), reduced libido, and fertility issues. In women, imbalances in estrogen levels can lead to irregular menstrual cycles, mood swings, and increased risk of certain health conditions such as endometriosis or breast cancer. 

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2123 Garnet Ave, Ste B, San Diego, CA 92109

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